Signal Transduction in Cancer

Turin, Italy
22-24 November 2018

Preliminary Programme

Thursday, 22 November

From Basic Research to Target Therapy

16:00-16:50

Plenary Lecture

Emilio Hirsch (UNITO-DBMSS, Turin)
Scaffold function of PI3Ks in cancer and cystic fibrosis

16:50-18:00

Four selected talks (each 15 min + 5 min discussion)

18:00-20:00

Aperitifs and Poster Session

Friday, 23 November

Signaling pathways in migration and invasion: from cells to human cancer

9:00-9:50

Plenary Lecture

Jim Norman (Cancer Research UK- Beatson Institute, Glasgow, Scotland)
The nuclear import machinery captures endosomes to drive depletion of nuclear G-actin, SRF/MRTF gene expression and invasive behaviour in cancer

9:50-10:30

Two selected talks (each 15 min + 5 min discussion)

10:30-11:00

Coffee break

11:00-11:40

Plenary Lecture

Enzo Medico (UNITO-IRCCS Candiolo, Turin)
In vivo cancer modeling with patient-derived xenografts: challenges and opportunities

11:40-12:20

Two selected talks (each 15 min + 5 min discussion)

12:20-14:30

Lunch and Poster Session

Signaling circuitries in tumor microenvironment

14:30-15:20

Plenary Lecture

Massimiliano Mazzone (Center for Cancer Biology, VIB, Leuven, Belgium)
Macrophage heterogeneity in cancer

15:20-16:30

Four selected talks (each 15 min + 5 min discussion)

16:30-17:00

Coffee break

17:00-19:00

Six selected talks (each 15 min + 5 min discussion)

20:00

Dinner

Saturday, 24 November

Signaling-metabolic rewiring in cancer

9:00-9:50

Plenary Lecture

Carlos Sebastiàn (IRCCS Candiolo, Turin)
SIRT6-dependent metabolic reprogramming as a driver of stem cell fate and tumorigenesis

9:50-10:30

Two selected talks (each 15 min + 5 min discussion)

10:30-11:00

Coffee break

11:00-12:20

Four selected talks (each 15 min + 5 min discussion)

12:20-12:30

Concluding remarks